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Jan 9, 2020
Autodesk SketchBook Pro 2020 has a quick installer that is direct from. you've never experienced the Autodesk SketchBook Pro 2020 before, and it offers a lot of new.A model of the 5'-flanking sequence of the neuropeptide Y receptor gene of the rat.
We have characterized the 5'-flanking sequence of the neuropeptide Y (NPY) receptor gene of the rat by comparing it with the sequences reported previously for the rabbit, the guinea pig, the human and the rat Y1 receptor genes. Our results show that the rat NPY receptor gene is encoded in three exons, containing 5'- and 3'-flanking sequences, and that the sequences 5' to the first exon share 80-85% homology to the Y1 receptor gene. In addition, there are at least two sequences 5' to the 3' exon which are encoded at a higher frequency in the rat NPY receptor gene than in the Y1 receptor gene. The homology of the sequences is highest between the 3' and 5' exons, and lowest within the exons themselves. The sequences are less well conserved in the 5' and 3' untranslated regions (UTRs). In the 5' UTR, the homology is greatest between the rat and the rabbit, intermediate between the rat and the guinea pig, and low between the rat and the human. The rat NPY receptor gene promoter lacks TATA and CCAAT boxes but contains two Sp-1/GC-rich motifs. One is an octamer sequence in the same orientation as the other two Sp-1/GC boxes present in the Y1 receptor gene. The second Sp-1/GC box, which is located immediately 5' to the TATA box, is identical to the box in the mouse apolipoprotein CII promoter and in the yeast 5' transcriptional control region. Sequence homology studies showed that this Sp-1/GC box in the NPY receptor gene is different from the Sp-1/GC box reported for the rat somatostatin receptor gene promoter. In addition, two Sp-1/GC boxes are present in the region 3' to the 3' exon of the rat NPY receptor gene be359ba680
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